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Plasmapheresis treatment of antibody-mediated rejection in an A2 donor to O pediatric liver transplant recipient.源自：Pediatr Transplant 2011 Feb;15 (1): E15-8.
Plasmapheresis treatment of antibody-mediated rejection in an A2 donor to O pediatric liver transplant recipient.
Martin T , Schwartz J , Demetris A , Comstock J , Lowichik A , Book L .
Division of GI/Hepatology and Liver Transplantation, Department of Pediatrics, University of Utah Hospital, Salt Lake City, UT 84113, USA. triscia.martin@hsc.utah.edu
Abstract
It is safe to transplant kidneys from blood group A2 donors into O recipients if the latter have low titers of anti-A antibodies. However, in liver transplantation, O and B recipients of A2 donor livers are not routinely screened for anti-blood group antibodies because of the immuno-absorptive capacity of the liver and the low incidence of antibody-mediated rejection. Herein, we report a rare case of combined cell and antibody-mediated rejection in a pediatric blood group O recipient of an A2 donor liver, and rescue of the allograft using PP and IVIG.
PMID: 19691524 [Pubmed - MEDLINE]